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Serological investigation on close contacts to patients with severe acute respiratory syndrome in an SARS outbreak / 中华流行病学杂志
Chinese Journal of Epidemiology ; (12): 867-869, 2004.
Artigo em Chinês | WPRIM | ID: wpr-325014
ABSTRACT
<p><b>OBJECTIVE</b>To study the evidence of severe acute respiratory syndrome (SARS) infection among close contacts to SARS patients and the level of sera IgG antibody in SARS cases.</p><p><b>METHODS</b>Specific IgG antibody against SARS-CoV in serum samples from contacts to patients, five months before an SARS outbreak in Beijing. Neutralized test, ELISA and immunity adherence test were studied. Samples were collected after clinical onset of patients or close contacts to patients, for 22 - 24 weeks. 19 close contacts and 13 cases were included in the study.</p><p><b>RESULTS</b>In close contacts, all tests were negative on three methods. All SARS cases were positive except one by immunity adherence test. The neutralized antibody levels were from 116 to 1203, with medium level of 143.</p><p><b>CONCLUSION</b>According to our survey, there was no latent infection among close contacts. IgG antibody in sera continued to be at higher levels among SARS cases 22 - 24 weeks after onset.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Sangue / Imunoglobulina G / Estudos Soroepidemiológicos / China / Epidemiologia / Surtos de Doenças / Síndrome Respiratória Aguda Grave / Coronavírus Relacionado à Síndrome Respiratória Aguda Grave / Alergia e Imunologia / Anticorpos Antivirais Limite: Feminino / Humanos / Masculino País/Região como assunto: Ásia Idioma: Chinês Revista: Chinese Journal of Epidemiology Ano de publicação: 2004 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Sangue / Imunoglobulina G / Estudos Soroepidemiológicos / China / Epidemiologia / Surtos de Doenças / Síndrome Respiratória Aguda Grave / Coronavírus Relacionado à Síndrome Respiratória Aguda Grave / Alergia e Imunologia / Anticorpos Antivirais Limite: Feminino / Humanos / Masculino País/Região como assunto: Ásia Idioma: Chinês Revista: Chinese Journal of Epidemiology Ano de publicação: 2004 Tipo de documento: Artigo