Study on the association between chronic hepatitis B cirrhosis and HLA-DRB1 * 1301,1302 allele / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 302-303, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-325560
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the association between the chronic hepatitis B cirrhosis and HLA-DRB1 * 1301,1302 gene.</p><p><b>METHODS</b>HLA-DRB1 * 1301,1302 allele in 27 patients with chronic hepatitis B cirrhosis and 30 patients with chronic hepatitis B was analyzed by using the polymerase chain reaction/sequence specific primer (PCR-SSP) technique.</p><p><b>RESULTS</b>The frenquency of HLA-DRB1 * 1301,1302 allele in the chronic hepatitis B cirrhosis group was markly higher than that in the chronic hepatitis B group.</p><p><b>CONCLUSION</b>HLA-DRB1 * 1301,1302 is closely associated with the suseptibility to chronic hepatitis cirrhosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Antígenos HLA-DR
/
Hepatite B Crônica
/
Alelos
/
Cadeias HLA-DRB1
/
Genética
/
Cirrose Hepática
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2009
Tipo de documento:
Artigo
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