Application of modified ultrafiltration in infants undergoing cardiac surgery with cardiopulmonary bypass / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 152-154, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-325604
ABSTRACT
<p><b>OBJECTIVE</b>Infants are usually subjected to serious complications after cardiac surgery with cardiopulmonary bypass (CPB). This study was conducted to evaluate the effects of a modified ultrafiltration technique (MUF) on infants undergoing cardiac surgery with CPB.</p><p><b>METHODS</b>A total of 261 infants less than 1 year old with congenital heart disease and who required CPB were randomized into receive MUF during CPB (n=205) or not (n=56, control group). Bypass duration, aortic cross-clamp duration, postoperative blood effluents and transfusions, mechanical ventilation duration following operation, and hematocrit and oxygenation index 24 hrs postoperatively were compared between the two groups.</p><p><b>RESULTS</b>No ultrafiltration-related complication was found in the MUF group. There were no significant differences in the duration of bypass and aortic cross-clamp between the two groups. Postoperative blood effluents and transfusions in the MFU group were significantly reduced (79.5+/-18.6 mL vs 57.3+/-15.4 mL and 78.1+/-32.5 mL vs 67.9+/-25.6 mL respectively) compared with the control group (P<0.05). The duration of mechanical ventilation following operation in the MFU group was shorter than that in the control group (28.6 +/- 9.1 hrs vs 32.3 +/- 8.7 hrs; P<0.05). MUF produced a significant improvement in hematocrit (34.6 +/- 3.7 min vs 29.8+/-2.8 min; P<0.01) and oxygenation index (275.2+/-39.1 vs 202.2+/-25.6; P<0.01) 24 hrs postoperatively when compared with the control group.</p><p><b>CONCLUSIONS</b>MFU can reduce postoperative bleeding and blood transfusions, improve pulmonary function and shorten the duration of mechanical ventilation in infants undergoing cardiac surgery with CPB.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Cirurgia Geral
/
Ultrafiltração
/
Ponte Cardiopulmonar
/
Cardiopatias Congênitas
/
Procedimentos Cirúrgicos Cardíacos
/
Métodos
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Feminino
/
Humanos
/
Masculino
/
Recém-Nascido
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2008
Tipo de documento:
Artigo
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