Prognostic Factors of Primary Gastric Lymphoma

ABSTRACT

BACKGROUND/AIM:Primary gastric lymphoma is uncommon, but the incidence of this malignancy is increasing. The purpose of this review was to find prognostic factors and establish an effective treatment principle for primary gastric lymphoma. METHODS: Between 1989 and 1996, 61 patients with primary gastric lymphoma were treated at the Asan Medical Center. Retrospective analysis and a pathologic review of these cases was performed. RESULTS: The mean age was 50 years (range16~81 years). There were 26 men and 35 women. The stages, according to the Ann Arbor staging system, were Stage IE ,IIE in 72.1% of the patients and stage IIIE, VIE in 27.9% of the patients. Forty (40) patients received operations38 surgical resections, 1 biopsy, and 1 bypass surgery. Forty-six (46) patients received chemotherpy, and among them, 26 received chemotherapy after surgical resection. The 5-year survival rate was 100% in stage IE, IIE and 51% in stage IIIE, IVE. The mean follow- up period was 25.6 months. CONCLUSION:Statistically significant prognostic factors were tumor stage and surgical resection.