Soft-tissue pyogenic infection in neonates caused by Staphylococcus aureus carrying Panton-Valentine leukocidin genes / 中华儿科杂志
Chinese Journal of Pediatrics
;
(12): 220-223, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-326182
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the pathogen causing soft-tissue pyogenic infection in neonate.</p><p><b>METHODS</b>The isolates of Staphylococcus aureus were obtained from liquor puris and blood by routine method. The Automated Microbiology Analyzer was used for identification and antimicrobial susceptibility test of the isolates. Panton-Valentine leukocidin (PVL) genes were determined by multiplex PCR in the isolates of Staphylococcus aureus. Multilocus sequence typing (MLST) was used to determine the sequence types (STs) of the isolates. The genotypes of SCCmec were also determined by another multiplex PCR in the isolates of methicillin-resistant Staphylococcus aureus (MRSA).</p><p><b>RESULTS</b>In 3 cases of neonate with soft-tissue pyogenic infection, 2 strains of Staphylococcus aureus isolated from liquor puris in 2 cases. 2 strains of Staphylococcus aureus were isolated from liquor puris and blood from another case. All 4 isolates were methicillin-resistant Staphylococcus aureus (MRSA) strains carrying PVL genes. Their SCCmec types were SCCmec IIIA. The STs of 4 isolates were ST88. The antimicrobial-resistance profile of the isolates were the same except erythromycin.</p><p><b>CONCLUSION</b>Soft-tissue pyogenic infection in the 3 neonates was caused by the same clone of MRSA carrying PVL genes.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Infecções Estafilocócicas
/
Toxinas Bacterianas
/
Infecções dos Tecidos Moles
/
Exotoxinas
/
Staphylococcus aureus Resistente à Meticilina
/
Tipagem de Sequências Multilocus
/
Genética
/
Leucocidinas
/
Microbiologia
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
/
Masculino
/
Recém-Nascido
Idioma:
Chinês
Revista:
Chinese Journal of Pediatrics
Ano de publicação:
2008
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS