Evaluation of surgical resection of pulmonary metastasis of trophoblastic tumour / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 418-421, 2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-327068
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the role of lung lobectomy in the patients of tumor with lung metastases.</p><p><b>METHODS</b>A total of 45 cases of trophoblastic tumor with pulmonary metastases treated by lung lobectomy from 1985-2002 at PUMC hospital was retrospectively analyzed. Seven cases were diagnosed as invasive mole and thirty-eight as choriocarcinoma.</p><p><b>RESULTS</b>Lung lobectomy was performed in all of these patients after several courses of chemotherapy. Seven cases of invasive mole reached complete remission. Eleven cases of choriocarcinoma with stage IIIa had received average 13 courses of chemotherapy, 10 of them reached complete remission. Seventeen cases of choriocarcinoma with stage IIIb had received average 14.3 courses of chemotherapy, 11 of them reached complete remission. Ten cases of choriocarcinoma with stage IV had received average 15 courses of chemotherapy, six of them reached complete remission. In the 45 patients, histologic examination disclosed haemorrhagic necrotic tissue in 27 patients, 17 of them reached complete remission (63%). Histologic examination also revealed fibrosis around the focus in 16 patients, 14 of them reached complete remission (88%). Tuberculosis was found in 2 patients.</p><p><b>CONCLUSIONS</b>Although the development of effective chemotherapy has resulted in improved survival of patients with gestational trophoblastic tumor, lung lobectomy remains an important adjunct treatment in a selected subset of patients. Pathological examinations can help to estimate the prognosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Pneumonectomia
/
Prognóstico
/
Cirurgia Geral
/
Neoplasias Uterinas
/
Vincristina
/
Protocolos de Quimioterapia Combinada Antineoplásica
/
Coriocarcinoma
/
Metotrexato
/
Estudos Retrospectivos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Adolescente
/
Adulto
/
Feminino
/
Humanos
/
Masculino
/
Gravidez
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2003
Tipo de documento:
Artigo
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