Advances in the research of mechanisms of promotion of vascularization by angiogenin and its application / 中华烧伤杂志
Chinese Journal of Burns
;
(6): 473-475, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-327373
ABSTRACT
Angiogenin, as a member of the ribonuclease superfamily, is an angiogenic protein. The angiogenic ability of angiogenin plays an important role in many physical and pathological processes. Angiogenin can induce endothelial cell migration, proliferation, tubulation, as well as inhibition of cellular apoptosis. Angiogenin can be used to modulate the angiogenetic process of tissue engineered constructions via local delivery. Furthermore, angiogenin can also be regarded as a biomarker for diagnostic evaluation of malignancy, or as a target for cancer therapy. This paper presents a comprehensive overview of the angiogenic mechanisms of angiogenin, as well as its potential application in the process of wound healing and treatment of ischemic diseases and malignancy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ribonuclease Pancreático
/
Movimento Celular
/
Neovascularização Fisiológica
/
Usos Terapêuticos
/
Neovascularização Patológica
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Burns
Ano de publicação:
2015
Tipo de documento:
Artigo
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