Sustained electrical stimulation of Bötzinger complex on phrenic nerve discharges in rabbits / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 385-388, 2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-330087
ABSTRACT
<p><b>AIM</b>To observe the effects of sustained electrical stimulation at Bötzinger complex (Böt. c) on phrenic nerve discharges.</p><p><b>METHODS</b>Sustained electrical stimulation (10--50 microA, 40-100 Hz, 0.3 ms, for 15-30 s) of Böt. C on 30 urethane anaesthetized, vagotomized, paralyzed and artificially ventilated rabbits.</p><p><b>RESULTS</b>Sustained electrical stimulation of Bot. C produced the inhibition or "inspiratory off-switch" of phrenic discharge during the stimulation. The inhibition of the phrenic discharges showed intensity and frequency dependence. Habituation was shown during the stimulation, showing the magnitude of the phrenic nerve discharge increased gradually. Post-stimulus rebound exhibited upon the cessation of the stimulation, showing the magnitude of the phrenic activity increased significantly. Short-term memory was shown in the habituation of the phrenic activity.</p><p><b>CONCLUSION</b>Non-associative learning is involved in the central control of respiratory modulation in the Böt. C and synaptic plasticity may exist in the respiratory neurons of Böt. C.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Nervo Frênico
/
Fisiologia
/
Estimulação Elétrica
/
Nervo Facial
/
Neurônios
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Applied Physiology
Ano de publicação:
2004
Tipo de documento:
Artigo
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