Effects of infrasound exposure on several enzymes activities of spleen and liver in rats / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 176-179, 2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-330153
ABSTRACT
<p><b>AIM</b>To investigate the changes of several enzymes activities in the spleen and liver of rats after exposure to 8 Hz 130 dB infrasound for different time.</p><p><b>METHODS</b>Thirty-five male SD rats were randomly divided into five groups. Rats of group 1 served as control, rats from group 2 to 5 were exposed to 8 Hz 130 dB infrasound, 2 hours per day, for 1 wk, 2 wk, 3 wk, and 4 wk, respectively. The changes of enzymes activities in spleen and liver of rats were observed.</p><p><b>RESULTS</b>Monoamine oxidase activities in spleen were significantly increased at 1 wk and 2 wk, it was decreased at 3 wk, and increased again at 4 wk (P < 0.05). There were no changes in the liver compared with the control group. Glutathione peroxides activities in spleen were significantly increased at 4 wk (P < 0.05) and it also increased in liver at 1 wk (P < 0.05). Superoxide dismutase activities in spleen were increased significantly from 1 wk to 4 wk, but there were no markedly changes in liver. The level of malondialdehyde in spleen were increased at 3 wk and 4 wk. In the liver, it were increased at 1 wk and 2 wk, and decreased at 3 wk, but it increased again at 4 wk (P < 0.05).</p><p><b>CONCLUSION</b>The results indicated that lipid peroxidation and oxygen free radicals in spleen and liver were increased after infrasound exposure and it might induce the damage in tissue or cells.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Baço
/
Superóxido Dismutase
/
Peroxidação de Lipídeos
/
Espécies Reativas de Oxigênio
/
Ratos Sprague-Dawley
/
Exposição Ambiental
/
Glutationa Peroxidase
/
Fígado
/
Malondialdeído
/
Metabolismo
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Applied Physiology
Ano de publicação:
2004
Tipo de documento:
Artigo
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