Study on hydrolysis kinetics of ginsenoside-Ro in alkaline medium and structural analysis of its hydrolyzate / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 867-872, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-330345
ABSTRACT
The ginsenoside-Ro is sensitive to be hydrolyzed in an alkaline medium. This paper investigated the hydrolysis kinetics of ginsenoside-Ro under different pH and temperature values. The results showed ginsenoside-Ro in alkaline solution followed pseudo-first-order reaction. Hydrolysis kinetics of ginsenoside-Ro has not been reported previously. The hydrolysis rate was independent of initial concentration. On the basis of UFLC-MS/MS, NMR, as well as chemical evidence,the structure of hydrolyzate was assigned as 3-O- [beta-D-glucuronopyranosyl- (1 --> 2) -beta-D-glucopyranosyl] -oleanolic acid.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Espectrometria de Massas
/
Medicamentos de Ervas Chinesas
/
Cinética
/
Espectroscopia de Ressonância Magnética
/
Estrutura Molecular
/
Química
/
Espectrometria de Massas por Ionização por Electrospray
/
Ginsenosídeos
/
Concentração de Íons de Hidrogênio
/
Hidrólise
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2014
Tipo de documento:
Artigo
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