Expression of mouse telomerase catalytic subunit mTERT gene in testis of SD rats and its significance / 华中科技大学学报(医学)(英德文版)
Journal of Huazhong University of Science and Technology (Medical Sciences)
;
(6): 288-290, 2003.
Artigo
em Inglês
| WPRIM
| ID: wpr-330927
ABSTRACT
To study the expression of mTERT gene in the testis of SD rats and its significance, in situ hybridization (ISH) techniques were used to detect the expression of telomerase gene mTERT mRNA in the testis of SD rats. The expression of mTERT was detectable in different-age male SD rats testis. There was a positive correlation between the expression of mTERT and the location of germ cells (spermatogonia, spermatocyte, spermatid). In Sertoli cells, leydig cell and spermatozoa, telomerase mTERT was not detected. Type A spermatogonia expressed the highest level of telomerase mTERT mRNA. Our results suggest that the expression of mTERT gene in the testis of SD rats is of lifetime and coincide with the telomerase activity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Espermátides
/
Espermatogênese
/
Espermatogônias
/
Espermatozoides
/
Testículo
/
RNA
/
Catálise
/
Diferenciação Celular
/
Ratos Sprague-Dawley
/
Regulação da Expressão Gênica no Desenvolvimento
Limite:
Animais
Idioma:
Inglês
Revista:
Journal of Huazhong University of Science and Technology (Medical Sciences)
Ano de publicação:
2003
Tipo de documento:
Artigo
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