Transitional cell carcinoma associated with aristolochic acid nephropathy: most common cancer in chronic hemodialysis patients in China / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 4460-4465, 2012.
Article
em En
| WPRIM
| ID: wpr-331353
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>The research of cancer in patients on hemodialysis (HD) in China has not been reported. The aim of this study was to investigate the clinical and histological features and outcomes of cancer in Chinese HD patients.</p><p><b>METHODS</b>The study subjects were 49 cancer patients (1.4%) out of 3448 end stage renal disease (ESRD) patients maintained on HD at China-Japan Friendship Hospital from October 1997 to July 2011.</p><p><b>RESULTS</b>Urinary tract cancer (74%) was the most common followed by gastrointestinal tract cancer (12%), breast cancer (6%), lung cancer (4%), thyroid cancer (2%), and hematologic cancer (2%). Thirty-three patients (67%) had urinary tract transitional cell carcinoma (TCC) and 29 of them had aristolochic acid nephropathy (AAN) as underlying disease. Death occurred in eight patients out of 49, and the survival rate of HD patients with cancer was similar to those without cancer (P = 0.120).</p><p><b>CONCLUSION</b>The urinary tract TCC is the most common cancer in HD patients with AAN in one of the centers of northern China.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Carcinoma de Células de Transição
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China
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Epidemiologia
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Estudos Retrospectivos
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Diálise Renal
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Neoplasias Urológicas
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Ácidos Aristolóquicos
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Nefropatias
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Metabolismo
Tipo de estudo:
Observational_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Chinese Medical Journal
Ano de publicação:
2012
Tipo de documento:
Article