Preparation of biodegradable and sustained release gel of tinidazole / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 87-90, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-331389
ABSTRACT
The objective of this study was to prepare a biodegradable poly (DL-lactide) injectable gel of tinidazole. The formulation parameters evaluated in this study included polymer molecular weight, polymer concentration, solvent and drug loading, and orthogonal design was used to optimize the formulation. The preferable formulation was that 30% (w/w) poly(DL-lactide) (MW is 5 700) dissolved in 70% (w/w) N-methyl-2-pyrrolidone with 4%-6% (w/w) tinidazole.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Poliésteres
/
Polímeros
/
Tinidazol
/
Portadores de Fármacos
/
Química
/
Tecnologia Farmacêutica
/
Ácido Láctico
/
Preparações de Ação Retardada
/
Géis
/
Métodos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2007
Tipo de documento:
Artigo
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