Anti-cervix-cancer effect of the co-immobilization of tumor necrosis factor-alpha and interferon-gamma / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 1303-1307, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-331425
ABSTRACT
To explore the effect of the co-photo-immobilization of Recombinant Human Interferon-r (IFN-gamma) and Recombinant Tumor Necrosis Factor (TNF-alpha) on the Hela cell cultivated in vitro. Co-immobilize the photoactive IFN-gamma and TNF-alpha on the polystyrene membrane; Cultivate the Hela cell on the cell culture polystyrene plate surface and set up the cultivation of the photo-immobilization IFN-gamma+TNF-alpha, Photo-immobilization IFN-gamma, nature (IFN-gamma, TNF-alpha, IFN-gamma+TNF-alpha). After 48 hours, the inhibition effect against Hela cells was studied in vitro by SEM and flow cytometry. It showed that the co-immobilization IFN-gamma+TNF-alpha has a more obvious inhibition effect on the Hela cell. And IFN-gamma can cooperate with TNF-alpha obviously.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Fotoquímica
/
Proteínas Recombinantes
/
Células HeLa
/
Química
/
Interferon gama
/
Fator de Necrose Tumoral alfa
/
Apoptose
/
Proliferação de Células
/
Sinergismo Farmacológico
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2006
Tipo de documento:
Artigo
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