Pathogenic diagnosis of an unexplained epidemic event of infectious diarrhea / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To determine the pathogen of an unexplained epidemic event of infectious diarrhea by laboratory diagnosis of suspected cases samples.</p><p><b>METHODS</b>28 samples from 28 suspected cases (22 fecal samples, 3 vomitus samples, 3 anus swab samples) were tested for Norovirus by RT-PCR. Sequencing and phylogenetic analysis were acomplished of 5 positive samples.</p><p><b>RESULTS</b>160 of 5694 population were ill with an attack rate of 2.81%. The peak period was 7-9, March. 14 of 28 samples were tested Norovirus positive.Sequencing and phylogenetic analysis showed Norovirus type GII/4 was the causative agent and it had highest identity (97. 9%) with epidemic strain 2006b.</p><p><b>CONCLUSION</b>The epidemic event ofinfectious diarrhea were caused by GII/4 Norovirus strains.</p>