Screening for new binding proteins which interact with BM2 of influenza B virus with yeast two-hybrid system / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 182-184, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-333067
ABSTRACT
<p><b>OBJECTIVE</b>To explore the role of BM2 protein in the life cycle of influenza B virus.</p><p><b>METHODS</b>The authors screened human kidney MATCHMAKER cDNA library for new binding partners of BM2 of influenza B virus by using the yeast two hybrid system with truncated BM2 (26-109 aa) as the bait.</p><p><b>RESULTS</b>Six positive plasmids encoding N-acetylneuraminate pyruvate lyase, angiopoietin 3, zinc finger protein 251, ribosomal protein S20, protein arginine N-methyltransferase 1 variant 1 (PRMT) and transcription factor-like 1 (TCFL1) were obtained.</p><p><b>CONCLUSION</b>The results suggest that BM2 may play an important role in the life cycle of influenza B virus.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Vírus da Influenza B
/
Plasmídeos
/
Proteína-Arginina N-Metiltransferases
/
Ligação Proteica
/
Proteínas Repressoras
/
Proteínas Ribossômicas
/
Fatores de Transcrição
/
Proteínas Virais
/
Biblioteca Gênica
/
Dedos de Zinco
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2005
Tipo de documento:
Artigo
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