The application of measuring arterial blood pressure to the startle conditioned reflex in chronic animal model / 中国应用生理学杂志

ABSTRACT

<p><b>AIM</b>To inquire a new credible animal model in studies of startle conditioned reflex.</p><p><b>METHODS</b>Through the trials of combining a conditioned stimulus (a tone) with an unconditioned stimulus(a foot shock), the startle responses were established in animals by conditioned stimulus. Arterial blood pressure were measured before and after blocking basolateral and lateral amygdala with lidocaine.</p><p><b>RESULTS</b>The blood pressure was increased by the conditioned stimulus after four days training. When the basolateral amygdala was blocked by lidocaine, the blood pressure was not increased by the conditioned stimulus.</p><p><b>CONCLUSION</b>The animal model used and verified in this experiment is a new credible chronic animal model in startle conditioned reflex by measuring arterial blood pressure.</p>