Bicarbonate secretion by the female reproductive tract and its impact on sperm fertilizing capacity / 生理学报
Acta Physiologica Sinica
;
(6): 115-124, 2005.
Artigo
em Inglês
| WPRIM
| ID: wpr-334197
ABSTRACT
The luminal fluid environment of the female reproductive tract is considered critical for the sperm to undergo a series of molecular events leading to the final acquisition of their fertilizing capacity. It has been shown that the fluid in the female reproductive tract contains high content of HCO3- and it plays an important role in sperm functions including sperm motility, capacitation, hyperactivation and acrosome reaction. This review summarizes the effects of HCO3- on sperm functions occurring in the female reproductive tract and discusses the transport mechanisms involved in mediating uterine HCO3- secretion. New evidence is also presented to show possible cause of female infertility due to defective HCO3- transporting mechanism.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Capacitação Espermática
/
Interações Espermatozoide-Óvulo
/
Útero
/
Bicarbonatos
/
Secreções Corporais
/
Fertilização
/
Metabolismo
Limite:
Animais
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Acta Physiologica Sinica
Ano de publicação:
2005
Tipo de documento:
Artigo
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