Molecular epidemiological study of human calicivirus infection in diarrhea children in autumn and winter at a hospital in Guangzhou / 南方医科大学学报
Journal of Southern Medical University
;
(12): 967-970, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-335018
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the epidemiological features of human calicivirus( HuCV) infection in children with diarrhea in a hospital in Guangzhou.</p><p><b>METHODS</b>Stool specimens were collected from children with viral diarrhea diagnosed between October, 2003 and January, 2004 and between October, 2004 and January, 2005. HuCV was detected by means of RT-PCR and sequence analysis of the PCR products.</p><p><b>RESULTS</b>Eighty specimens positive for Norwalk-like viruses (NLVs) were identified from 648 stool specimens, with a positivity rate of 12.35%, and sapporo-like viruses (SLVs) were identified in 2 specimens (0.31%). The monthly NLV positivity rate was 11.74% (Oct.), 14.16% (Nov.), 9. 09% (Dec.) and 13.95% (Jan.), respectively, showing no significant variation in these months. NLVs mainly infected children below 2 years old. Twenty-two strains of NLVs were sequenced and analyzed, and 21 of them were identified as GII and the genotype of 1 strain could not be determined. The prevalent viral population were GII-3 and GII-4 in 2003 and was GII-4 in 2004, and both of the SLVs belong to GI-1.</p><p><b>CONCLUSION</b>NLVs is one of the important pathogens causing sporadic acute gastroenteritis in children admitted in the hospital in Guangzhou, and the prevalent strains are GII-3 and GII-4 , but different prevalent strains are possible in different periods.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Filogenia
/
Estações do Ano
/
Virologia
/
Caliciviridae
/
RNA Viral
/
Dados de Sequência Molecular
/
China
/
Epidemiologia
/
Prevalência
/
Classificação
Tipo de estudo:
Estudo de prevalência
Limite:
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2006
Tipo de documento:
Artigo
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