Antinociceptive activity of Ricinus communis L. leaves
Asian Pacific Journal of Tropical Biomedicine
;
(12): 139-141, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-335052
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the antinociceptive activity of the methanol extract of Ricinus communis leaves (MRCL).</p><p><b>METHODS</b>Antinociceptive activity was evaluated using acetic acid induced writhing test, formalin induced paw licking and tail immersion method in mice at doses of 100, 125 and 150 mg/kg bw.</p><p><b>RESULTS</b>The results indicated that MRCL exhibited considerable antinociceptive activity against three classical models of pain in mice. Preliminary phytochemical analysis suggested the presence of saponin, steroids and alkaloids.</p><p><b>CONCLUSIONS</b>It can be concluded that MRCL possesses antinociceptive potential that may be due to saponin, steroids and alkaloids in it.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Dor
/
Ricinus
/
Saponinas
/
Extratos Vegetais
/
Química
/
Folhas de Planta
/
Tratamento Farmacológico
/
Alcaloides
/
Analgésicos
Limite:
Animais
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Asian Pacific Journal of Tropical Biomedicine
Ano de publicação:
2011
Tipo de documento:
Artigo
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