Effectiveness of Varenicline with counseling programs on smoking cessation in a targeted clinical setting in China / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 1349-1353, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-335228
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the effectiveness of Varenicline for smoking cessation in a community-based smoking-cessation-clinic (SCC) in Chinese smokers.</p><p><b>METHODS</b>A prospective observational study was conducted in Beijing, China. 799 smokers (762 men and 37 women) were assessed on data gathered from structured questionnaires at baseline and follow up programs at 1, 3 and 6 months. Trained physician counselors provided free individual counseling and follow-up interviews with brief counseling for all the subjects. 272 subjects were additionally prescribed Varenicline according to their own choice and reported data were compared to those without Varenicline. Outcomes were self-reported, regarding the 7-day point prevalence on abstinence rate and continuous abstinence rates at 1, 3 and 6 month follow-up periods.</p><p><b>RESULTS</b>At 6-month and by intention-to-treat, the 7-day point prevalence on abstinence rate with Varenicline and counseling, was significantly higher than the group with counseling only (34.6% versus 23.1%; OR = 1.75, 95% CI 1.27-2.42;P < 0.001). The 3-month continuous abstinence rate at 6 month was higher in the group with Varenicline(31.3% versus 18.2% ;OR = 2.04, 95% CI1.46-2.86;P < 0.001). Varenicline also showed better outcomes at 1 and 3 month follow-up.</p><p><b>CONCLUSION</b>Varenicline prescription in the smoking cessation clinic appeared to be effective that doubled the rates of quitting among Chinese smokers in the practice at a community-based SCC.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Quinoxalinas
/
Terapêutica
/
Tabagismo
/
Benzazepinas
/
China
/
Estudos Prospectivos
/
Abandono do Hábito de Fumar
/
Agonistas Nicotínicos
/
Aconselhamento
/
Usos Terapêuticos
Tipo de estudo:
Estudos de avaliação
/
Estudo observacional
/
Pesquisa qualitativa
Limite:
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Epidemiology
Ano de publicação:
2014
Tipo de documento:
Artigo
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