Subcutaneous implantation of embryonic skin cells to construct a model of hair development in nude mice / 南方医科大学学报

ABSTRACT

<p><b>OBJECTIVE</b>To observe the hair development after subcutaneous implantation of embryonic skin cells in nude mice, and construct a model of hair development.</p><p><b>METHODS</b>Dermal and epidermal cells isolated from embryonic mouse skin were mixed at a given ratio and injected subcutaneously in nude mice, and hair formation after the implantation was observed under a microscope.</p><p><b>RESULTS</b>Formation of the hair follicles and fibers under the skin of the recipient nude mice and emergence of the hair shaft were observed microscopically.</p><p><b>CONCLUSION</b>Embryonic skin cells be used to construct a complete model of hair development after implantation in vivo.</p>