Changes of peripheral blood chromosomal centromere aberration in patients with cytomegalovirus infection after anti-viral treatment / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1846-1847, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-336069
ABSTRACT
<p><b>OBJECTIVE</b>To study the changes of peripheral blood chromosomal centromere aberration in patents with cytomegalovirus (CMV) infection after anti-viral treatment.</p><p><b>METHODS</b>Sixty-two patients with early spontaneous abortion and CMV infection analyzed for their peripheral blood chromosomal centromere using simultaneous silver staining before and after anti-viral treatment.</p><p><b>RESULTS</b>The patients with CMV infection had high rate of centromere aberration, which was decreased significantly after anti-viral treatment (P<0.0001).</p><p><b>CONCLUSION</b>CMV infection is a risk factor for peripheral blood chromosomal centrimere aberration. Anti-viral treatment can decrease the rate of centrimere aberration aberration. Detection of peripheral blood chromosomal centrimere aberration allows the assessment of the severity of infection and the condition after treatment.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Antivirais
/
Complicações Infecciosas na Gravidez
/
Sangue
/
Aborto Espontâneo
/
Centrômero
/
Aberrações Cromossômicas
/
Infecções por Citomegalovirus
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Genética
Tipo de estudo:
Fatores de risco
Limite:
Adulto
/
Feminino
/
Humanos
/
Gravidez
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2009
Tipo de documento:
Artigo
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