Effect of wet dressing with Jingjielianqiao decoction on healing of acute radiation-induced skin ulcers in rats / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1600-1603, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-336131
ABSTRACT
<p><b>OBJECTIVE</b>To observe the pharmacodynamics of Jingjielianqiao decoction in promoting the healing of acute radiation-induced skin ulcers in mice.</p><p><b>METHODS</b>Skin ulcers were induced in mice by radiation, and Jingjielianqiao decoction, rivanol or normal saline was applied for the treatment. The swelling of the legs was measured in mice using volumetric method, and the ulcer area after treatment was compared among the 3 groups.</p><p><b>RESULTS</b>No significant difference was found in the anti-inflammatory effects between Jingjielianqiao decoction group and rivanol group (P>0.05), but a significant difference was noted between Jingjielianqiao decoction group and normal saline group and also between rivanol group and normal saline group (P<0.01). Significant differences were observed in the ulcer healing among the 3 groups (P<0.01).</p><p><b>CONCLUSION</b>Jingjielianqiao decoction can significantly suppress radiation-induced acute inflammation and shows better effect than rivanol in promoting the healing of acute radiation-induced skin ulcer in rats.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Radiodermite
/
Úlcera Cutânea
/
Cicatrização
/
Medicamentos de Ervas Chinesas
/
Ratos Wistar
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Fitoterapia
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2010
Tipo de documento:
Artigo
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