Research progress of protein tyrosine phosphatase SHP-2 / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 581-585, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-336748
ABSTRACT
The Src homology-2 domain-containing phosphatase SHP-2 encoded by PTPN11 is an essential component in several signaling pathways.Different types of mutation in SHP-2 have been confirmed in several types of leukemia and solid tumors. Elucidation of the events underlying Shp2-evoked transformation may provide new insights into the novel targets for anti-cancer therapy.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Química
/
Proteína Tirosina Fosfatase não Receptora Tipo 11
/
Metabolismo
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2012
Tipo de documento:
Artigo
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