Prolonged hepatitis and jaundice: a rare complication of paediatric Epstein-Barr virus infection
Singapore medical journal
;
: e112-5, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-337119
ABSTRACT
We herein report the case of a 14-year-old girl with Epstein-Barr virus (EBV) infectious mononucleosis who developed prolonged hepatitis and jaundice. At presentation, she had tender hepatomegaly with a markedly deranged liver function test. Abdominal ultrasonography showed hepatomegaly and a thickened gallbladder wall. During the subsequent 11 weeks, her transaminases showed two further peaks, which corresponded with clinical deterioration. Her highest alanine transaminase level was 1,795 µ/L and total bilirubin level was 154 µmol/L. She recovered fully with conservative management. EBV-related liver involvement is typically mild and self-limiting. We believe that tender hepatomegaly and gallbladder thickening may be important predictors of significant liver involvement. Although multiple transaminase peaks may occur, we do not consider this an indication for antiviral or immunosuppressive therapy. In the absence of strong evidence supporting the use of any specific therapy, we recommend a conservative approach for an immunocompetent patient.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Antivirais
/
Patologia
/
Bilirrubina
/
Sangue
/
Diagnóstico por Imagem
/
China
/
Ultrassonografia
/
Resultado do Tratamento
/
Infecções por Vírus Epstein-Barr
/
Usos Terapêuticos
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Adolescente
/
Feminino
/
Humanos
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Singapore medical journal
Ano de publicação:
2015
Tipo de documento:
Artigo
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