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Comparison of pragmatic clinical trials and explanatory clinical trials / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine ; (12): 161-164, 2009.
Artigo em Chinês | WPRIM | ID: wpr-337525
ABSTRACT
Clinical trials are often designed as either pragmatic or explanatory. The pragmatic clinical trials are generally used for measuring the effectiveness of a treatment in common clinical practice, while the explanatory trial for measuring the efficacy of a treatment under ideal conditions. Since the methods concerning pragmatic clinical trials are less introduced in China, its archetypal features, advantages and limitations were introduced in this paper. And a current study of pragmatic clinical trials on using acpuncture for treatment of low back pain carried out in German was taken as an example to illustrate the practical methods concretely. The key steps of the design were presented in detail, and reasonable suggestions about the problems often encountered in the trial, as well as how to balance the internal and external validity, outcome measurement, etc., were offered.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Padrões de Referência / Tomada de Decisões Gerenciais / Ensaios Clínicos como Assunto / Interpretação Estatística de Dados / Métodos Tipo de estudo: Estudo prognóstico Limite: Humanos Idioma: Chinês Revista: Chinese Journal of Integrated Traditional and Western Medicine Ano de publicação: 2009 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Padrões de Referência / Tomada de Decisões Gerenciais / Ensaios Clínicos como Assunto / Interpretação Estatística de Dados / Métodos Tipo de estudo: Estudo prognóstico Limite: Humanos Idioma: Chinês Revista: Chinese Journal of Integrated Traditional and Western Medicine Ano de publicação: 2009 Tipo de documento: Artigo