Immunophenotypic characteristics of multiple myeloma cells / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 226-228, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-337604
ABSTRACT
To investigate the immunophenotypic characteristics of multiple myeloma (MM) cells, 20 bone marrow samples from patients with multiple myeloma were analyzed by flow cytometry with three-color direct immunofluorescence staining. Results showed that all of myeloma cells expressed bright CD38, dim or negative CD45 and negative CD19. Most of the cells were CD56(+) and a small portions were ckappa(+) or clambda(+), or CD20(+). The phenotypes of normal plasmocyte, CD19(+) and CD56(-), except CD56(-) in one-third samples, were not appeared in all detected samples. It was concluded that the surface marker analysis of myeloma cells is a useful tool for diagnosis and further evaluating prognosis of multiple myeloma.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Células da Medula Óssea
/
Glicoproteínas de Membrana
/
Antígenos CD
/
Imunofenotipagem
/
Antígenos Comuns de Leucócito
/
Antígeno CD56
/
Antígenos CD20
/
Antígenos CD19
/
ADP-Ribosil Ciclase
/
Alergia e Imunologia
Tipo de estudo:
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2002
Tipo de documento:
Artigo
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