Human umbilical cord blood hematopoietic stem/progenitor cells can grow up in the mouse liver / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 391-394, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-337661
ABSTRACT
The biological characterization, differentiation and regeneration of hepatic stem/progenitor cells are the one of very active and interested fields. In this report, intravenous injection of human umbilical cord blood (HUCB) cells into the BALB/c-nu and SCID mice, an animal model for transplantation and liver injury, was reported. Using of flow cytometry and tissue typing (HLA), it was found that the HUCB cells were survived in mouse liver for 9 weeks. After separation from perfused liver, HUCB cells were detected by hematopoietic colonies (CFU-GEM M) in hepatocyte culture. It was concluded that the transplanted HUCB hematopoietic stem/progenitor cells can be survived in the liver over a long period of time.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Células-Tronco Hematopoéticas
/
Antígenos HLA-DR
/
Divisão Celular
/
Camundongos SCID
/
Transplante de Células-Tronco Hematopoéticas
/
Biologia Celular
/
Sangue Fetal
/
Citometria de Fluxo
/
Fígado
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2002
Tipo de documento:
Artigo
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