Severe Osteomyelitis as a Complication of Tokyo-172 BCG Vaccination
Journal of Korean Medical Science
;
: 221-224, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-33790
ABSTRACT
The bacilli Calmette-Guerin (BCG) Tokyo-172 strain was considered to exhibit good protective efficacy with a low rate of unfavorable side effects. However, we describe a rare case of BCG osteomyelitis developed in an immunocompetent host who was given with BCG Tokyo-172 vaccine on the left upper arm by multipuncture method. A 9-month-old girl presented with progressive inability to move her right elbow and had radiographic evidence of septic elbow combined with osteomyelitis of right distal humerus. A biopsy from the site revealed chronic caseating granulomatous inflammation, positive for BCG Tokyo-172 strain on the multiplex polymerase chain reaction. The child had to undergo second surgical debridements and oral antituberculosis chemotherapy. There were no sequelae after 2 yr of follow-up. This complication, although uncommon, should be considered in the appropriate clinical setting.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteomielite
/
DNA Bacteriano
/
Imageamento por Ressonância Magnética
/
Vacina BCG
/
Reação em Cadeia da Polimerase Multiplex
/
Mycobacterium bovis
/
Antituberculosos
Limite:
Feminino
/
Humanos
/
Lactente
Idioma:
Inglês
Revista:
Journal of Korean Medical Science
Ano de publicação:
2012
Tipo de documento:
Artigo
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