Genetic polymorphism of FMO3 and its role in drug metabolism and toxicity / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 2701-2705, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-337905
ABSTRACT
The flavin-containing monooxygenase 3 (FMO3) is an important hepatic microsomal enzyme. Numerous mutations of FMO3 gene have been reported, and polymorphic varients of the gene have been identified. Several studies indicated that variability in the expression of FMO3 involved in some nitrogen, or sulfur-containing durg metabolism. This review summarizes the genetic polymorphism of FMO3 and its role in drug metabolism and toxicity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxigenases
/
Polimorfismo Genético
/
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Genética
Limite:
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2015
Tipo de documento:
Artigo
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