Chemical constituents contained in Salvia castanea / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate chemical constituents contained in Salvia castanea.</p><p><b>METHOD</b>The compounds were separated and purified by silica gel, macroporous resin, RP-C18 and Sephadex LH-20 column chromatography. The structures were identified on the basis of physicochemical property and spectral data.</p><p><b>RESULT</b>Nineteen compounds were separated and identified as tanshinone II(A) (1) , tanshinone II(B) (2), hydroxytanshinone II(A) (3), tanshinone I(4), dihydrotanshinone I(5), cryptotanshinone (6) , neotanshinone A(7) , neotanshinone B(8) , tanshinoldehyde(9), przewaquinone A(10), przewaquinone B(11), sugiol(12), caffeic acid(13), rosmarinci acid(14), ethylrosmarinate(15), lithospermic acid(16), pro-lithospermic acid ( 17) , protocatechualdehyde (18), and danshensu(19).</p><p><b>CONCLUSION</b>Compounds 2, 3, 7-13 and 15-19 were separated from S. castanea for the first time.</p>