Dose-effect relationship between premature chromosome and irradiation dose / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 714-717, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-338934
ABSTRACT
<p><b>OBJECTIVE</b>To explore the dose-effect relationship between premature chromosome condensation induced by Calyculin A and irradiation dose.</p><p><b>METHODS</b>The human peripheral blood was irradiated by (137)Cs gamma radial. The irradiation dose included 0, 0.5, 1.0, 2.0, 3.0, 4.0, 5.0 Gy. The premature chromosome condensation induced by Calyculin A was observed, and dyed by centromeric banding.</p><p><b>RESULTS</b>There was the quadratic relation between the total aberration, fragment, dicentric+centric ring (dic+r) ration and irradiation dose.</p><p><b>CONCLUSION</b>Premature chromosome condensation induced by Calyculin A can be used as a biodosimetry.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oxazóis
/
Farmacologia
/
Efeitos da Radiação
/
Linfócitos
/
Linhagem Celular
/
Aberrações Cromossômicas
/
Bandeamento Cromossômico
/
Cromossomos
/
Relação Dose-Resposta à Radiação
/
Raios gama
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Ano de publicação:
2007
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS