Relationship of serum prostate-specific antigen and alkaline phosphatase levels with bone metastases in patients with prostate cancer / 中华男科学杂志
National Journal of Andrology
;
(12): 825-827, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-339415
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relation of serum prostate-specific antigen (PSA) and alkaline phosphatase (ALP) levels to bone metastases in patients with prostate cancer.</p><p><b>METHODS</b>We made a retrospective study of 96 cases of prostate cancer with (29 cases ) and without (67 cases ) bone metastases and evaluated their initial levels of serum PSA and ALP as well as the radionuclide bone scan findings.</p><p><b>RESULTS</b>The median concentrations of serum PSA and ALP were both in the bone scan-positive patients statistically higher than in those the negative ones (P < 0.01). The percentages of the bone scan-positive patients with PSA > 20 microg/L or ALP > 90 U/L were also higher than those with PSA < 20 microg/L or ALP < 90 U/L (P < 0.01).</p><p><b>CONCLUSION</b>Prostate cancer patients with bone metastases have higher levels of PSA and ALP than those without. Radionuclide bone scan is necessary when the serum PSA level is > 20 microg/L and/or ALP level > 90 U/L.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Neoplasias da Próstata
/
Sangue
/
Neoplasias Ósseas
/
Diagnóstico por Imagem
/
Cintilografia
/
Biomarcadores Tumorais
/
Estudos Retrospectivos
/
Sensibilidade e Especificidade
/
Antígeno Prostático Específico
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Idoso
/
Aged80
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2005
Tipo de documento:
Artigo
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