Gene expression profiling in porcine fetal thymus / 基因组蛋白质组与生物信息学报·英文版
Genomics, Proteomics & Bioinformatics
;
(4): 171-172, 2003.
Artigo
em Inglês
| WPRIM
| ID: wpr-339510
ABSTRACT
To obtain an initial overview of gene diversity and expression pattern in porcine thymus, 11,712 ESTs (Expressed Sequence Tags) from 100-day-old porcine thymus (FTY) were sequenced and 7,071 cleaned ESTs were used for gene expression analysis. Clustered by the PHRAP program, 959 contigs and 3,074 singlets were obtained. Blast search showed that 806 contigs and 1,669 singlets (totally 5,442 ESTs) had homologues in GenBank and 1,629 ESTs were novel. According to the Gene Ontology classification, 36.99% ESTs were cataloged into the gene expression group, indicating that although the functional gene (18.78% in defense group) of thymus is expressed in a certain degree, the 100-day-old porcine thymus still exists in a developmental stage. Comparative analysis showed that the gene expression pattern of the 100-day-old porcine thymus is similar to that of the human infant thymus.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Timo
/
Variação Genética
/
Análise de Sequência de DNA
/
Biologia Computacional
/
Etiquetas de Sequências Expressas
/
Perfilação da Expressão Gênica
/
Sus scrofa
/
Feto
/
Genética
/
Metabolismo
Limite:
Animais
Idioma:
Inglês
Revista:
Genomics, Proteomics & Bioinformatics
Ano de publicação:
2003
Tipo de documento:
Artigo
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