A Case of Acute Disseminated Encephalomyelitis Presenting with Bilateral Optic Neuritis associated with Mycoplasma pneumoniae / 대한소아신경학회지
Journal of the Korean Child Neurology Society
; (4): 222-228, 2008.
Article
em En
| WPRIM
| ID: wpr-33985
Biblioteca responsável:
WPRO
ABSTRACT
Mycoplasma pneumoniae(M. pneumoniae) is a well-known human respiratory pathogen. It also affects various organ systems and causes extrapulmonary complications, including neurologic, cutaneous, hematologic and ophthalmologic complications. M. pneumoniae has been implicated in a number of immune-mediated neurological diseases, such as ADEM, Gullian- Barre syndrome, and transverse myelitis. We present a 5-year-old boy with bilateral optic neuritis related to ADEM and pruritic skin lesions simultaneously associated with M. pneumoniae infection. He developed a headache with decreased activity six weeks before admission. He had no respiratory symptoms. Cerebral MRI showed multiple bilateral subcortical white matter lesions, suggesting a radiologic diagnosis of ADEM. M. pneumoniae was positive serologically. The cerebrospinal fluid polymerase chain reaction for M. pneumoniae was negative. The treatment with intravenous high-dose steroids and oral clarithromycin resulted in the rapid recovery of the patients visual and cutaneous problems. He was found to have returned to his normal conditions in the follow-up examination. We believe that immune-mediated injury can explain all the clinical manifestations of our case, which are ADEM-associated optic neuritis and cutaneous lesions.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Pneumonia
/
Pneumonia por Mycoplasma
/
Pele
/
Manifestações Cutâneas
/
Esteroides
/
Pré-Escolar
/
Neurite Óptica
/
Reação em Cadeia da Polimerase
/
Seguimentos
/
Claritromicina
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Revista:
Journal of the Korean Child Neurology Society
Ano de publicação:
2008
Tipo de documento:
Article