Research progress in the structure and fuction of Orthopoxvirus host range genes / 病毒学报
Chinese Journal of Virology
;
(6): 437-441, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-339931
ABSTRACT
Orthopoxvirus vector has a broad prospect in recombinant vaccine research, but the rarely severe side-effect impedes its development. Vaccinia virus and Cowpox virus of Orthopoxvirus have broad host range, and they have typical host range genes as K1L, CP77 and C7L. These three genes affect host range of Vaccinia virus, disturb the cell signaling pathways, suppress immune response and are related to virulence.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Vaccinia virus
/
Proteínas Virais
/
Virulência
/
Vacinas Virais
/
Vacinas Sintéticas
/
Transdução de Sinais
/
Vírus da Varíola Bovina
/
Linhagem Celular
/
Orthopoxvirus
Idioma:
Chinês
Revista:
Chinese Journal of Virology
Ano de publicação:
2013
Tipo de documento:
Artigo
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