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Virological characterization of influenza B virus in mainland China during 2011-2012 / 病毒学报
Chinese Journal of Virology ; (6): 32-38, 2013.
Artigo em Chinês | WPRIM | ID: wpr-339978
ABSTRACT
In order to understand the prevalence and variation of influenza B viruses, the antigenic and genetic characteristics of influenza B viruses circulating in Mainland China during April, 2011 to March, 2012 were analyzed. The results showed the B Victoria lineage viruses were much more prevalent than B Yamagata lineage during this period, phylogenetic analysis showed vast majority of Victoria lineage viruses belong to genetic group 1, intra-clade reassortant between HA1 and NA gene was identified in a minor proportion of the viruses. 72.8% of the B/Victoria-lineage viruses were antigenically closely related to the vaccine strain B/Brisbane/60/2008. B Yamagata component was not included in the trivalent influenza vaccine in China during the study period, however vast majority of B Yamagata lineage viruses were antigenically and genetically closely related to the representative virus B/Hubei-Wujiagang/158/2009(97.8%) and B/Sichuan-Anyue/139/2011(85.2%) in China, reassortant between HA1 and NA was not identified in B Yamagata lineage viruses. Overall, the predominant circulating influenza B viruses in 2011-2012 season in China were matched by current influenza vaccine and the selected representative viruses were proved to represent the antigenic and genetic characteristics of the circulating viruses.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Vírus da Influenza B / Filogenia / Fatores de Tempo / Vacinas contra Influenza / China / Classificação / Alergia e Imunologia / Genética Tipo de estudo: Estudo prognóstico Limite: Humanos País/Região como assunto: Ásia Idioma: Chinês Revista: Chinese Journal of Virology Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Vírus da Influenza B / Filogenia / Fatores de Tempo / Vacinas contra Influenza / China / Classificação / Alergia e Imunologia / Genética Tipo de estudo: Estudo prognóstico Limite: Humanos País/Região como assunto: Ásia Idioma: Chinês Revista: Chinese Journal of Virology Ano de publicação: 2013 Tipo de documento: Artigo