Inflammatory reaction and alterations of pulmonary surfactant in Pseudomonas Aeruginosa pneumonia in immunocompromised rats / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 1099-1100, 2002.
Artigo
em Inglês
| WPRIM
| ID: wpr-340375
ABSTRACT
Pulmonary surfactant ( PS ) compromises lipids and surfactant proteins (SP) and lines on the alveolar air-liquid interface. It can reduce surface tension, prevent alveoli from collapse and reduce alveoli edema by disaturated dipalmitoylphosphatidylcholine. It also modulates the pulmonary immunology by SP-A and SP-D. In this study,we established a rat model of immunocompromised host (ICH) with pulmonary infection of Pseudomonas aeruginosa (P. aeruginosa), then studied its pulmonary inflammatory reaction and analyzed the concentration of lipids and SP-A in bronchoalveolar lavage fluid (BALF) during infection.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Proteolipídeos
/
Infecções por Pseudomonas
/
Surfactantes Pulmonares
/
Líquido da Lavagem Broncoalveolar
/
Química
/
Ratos Sprague-Dawley
/
Pneumonia Bacteriana
/
Proteína A Associada a Surfactante Pulmonar
/
Proteínas Associadas a Surfactantes Pulmonares
Limite:
Animais
Idioma:
Inglês
Revista:
Chinese Medical Journal
Ano de publicação:
2002
Tipo de documento:
Artigo
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