A new model for survival assessment based on the Chinese liver transplantation patients with hepatocellular carcinoma / 中华外科杂志
Chinese Journal of Surgery
;
(12): 1023-1026, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-340868
ABSTRACT
<p><b>OBJECTIVE</b>To establish a new model for liver transplantation recipients with hepatocellular carcinoma (HCC) and validate the feasibility of it.</p><p><b>METHODS</b>From February 1999 to June 2005, clinical data of 130 liver cancer patients who accepted liver transplantation were collected. Screening the pretransplant factors correlated with post-transplant survival using COX proportional-hazards regression, and establishing the assessment model. Finally, the area under the receiver operating characteristic curve (AUC ROC) were used to compare the validity of the new model with MELD.</p><p><b>RESULTS</b>Screened by the COX model, serum concentrations of alkaline phosphatase, alphafetoprotein, sodium and the number of tumor nodule were significantly related with post-transplant survival. The new model with these four variables had greater ability to assess post-transplant recipients' outcomes, however, the MELD had not evaluation capacity.</p><p><b>CONCLUSION</b>The established new model has a better ability to assess the risk of post-transplant mortality.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sódio
/
Cirurgia Geral
/
Sangue
/
Alfa-Fetoproteínas
/
Modelos de Riscos Proporcionais
/
Análise de Sobrevida
/
China
/
Estudos de Viabilidade
/
Reprodutibilidade dos Testes
/
Transplante de Fígado
Tipo de estudo:
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Surgery
Ano de publicação:
2007
Tipo de documento:
Artigo
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