Association of the Parathyroid Adenoma Volume and the Biochemical Parameters in Primary Hyperparathyroidism
Endocrinology and Metabolism
;
: 62-66, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-34102
ABSTRACT
BACKGROUND:
The objective of this study is to demonstrate the relationship between the volume of a parathyroid adenoma and the preoperative biochemical parameters in patients undergoing surgery for primary hyperparathyroidism.METHODS:
The medical records of 68 patients who underwent a parathyroidectomy for a single parathyroid adenoma were retrospectively reviewed. The volume of the adenoma was estimated using its measured size and a mathematical formula. The correlation between the volume of the parathyroid adenoma and the preoperative laboratory data was assessed.RESULTS:
There were no correlations between the estimated volume of the adenoma and the serum calcium, alkaline phosphatase and parathyroid hormone levels. However, the volume of the adenoma was associated with the preoperative level of serum phosphorus. After excluding 5 adenomas with cystic degeneration, a positive correlation was noted between the adenoma volume and the preoperative levels of alkaline phosphatase and parathyroid hormone.CONCLUSION:
The preoperative serum levels of calcium, alkaline phosphatase and parathyroid hormone are of limited use to predict the volume of the parathyroid adenoma in patients with a single parathyroid adenoma. We suggest that the absence of a correlation between the volume of the adenoma and the biochemical parameters can be attributed to the cystic degeneration of the adenomas.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Hormônio Paratireóideo
/
Neoplasias das Paratireoides
/
Fósforo
/
Adenoma
/
Prontuários Médicos
/
Cálcio
/
Estudos Retrospectivos
/
Paratireoidectomia
/
Fosfatase Alcalina
/
Hiperparatireoidismo Primário
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Endocrinology and Metabolism
Ano de publicação:
2011
Tipo de documento:
Artigo
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