Polymorphism of 17 short tandem repeat Loci of Tibetan minority ethnic group from Lhasa / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 397-401, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-341395
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the polymorphism of 17 short tandem repeat (STR) loci of Tibetan minority ethnic group from Lhasa.</p><p><b>METHODS</b>Blood samples were obtained from 132 unrelated Tibetan individuals from Lhasa. DNA templates were screened by home-made AGCU17+1 kit and 3130XL genetic analyzer. Genotyping was performed using GeneMapper software (version 3.2).</p><p><b>RESULTS</b>The allele frequencies of 17 STR loci ranged 0.0038-0.5720, and the power of discrimination ranged 0.779-0.979, the power of exclusion ranged 0.327-0.737, the polymorphism information contents ranged 0.538-0.910, and the heterozygosity ranged 0.629-0.871. The cumulative coupling probability was 3.93 × 10(-20), and the cumulative power of exclusion was 0.9999995234. Of 17 STR loci, Penta E and D6S1043 had the highest polymorphism indicators, while TPOX had the lowest.</p><p><b>CONCLUSION</b>The 17 STR loci used in this study are highly polymorphism in Tibetan minority ethnic group from Lhasa and fit for the population genetic study and forensic cases.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Polimorfismo Genético
/
Etnicidade
/
Tibet
/
Repetições de Microssatélites
/
Povo Asiático
/
Frequência do Gene
/
Genética
/
Genótipo
/
Grupos Minoritários
Limite:
Humanos
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2011
Tipo de documento:
Artigo
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