Role of transrectal real-time tissue elastography in the diagnosis of prostate cancer / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 175-179, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-341436
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the role of transrectal real-time tissue elastography (TRTE) in the diagnosis of prostate cancer (PCa).</p><p><b>METHODS</b>Eighty-four patients with suspected PCa and scheduled for prostate biopsies underwent TRTE, digital rectal examination (DRE), transrectal ultrasonography (TRUS), and magnetic resonance imaging (MRI). The findings of TRTE were compared with those of other examinations and pathological findings.</p><p><b>RESULTS</b>Of these 84 patients, 36 had benign lesions and 48 had PCa. The diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive value were 91.7%, 72.2%, 83.3%, 81.5%, and 86.7% for TRTE and 85.4%ì63.9%ì76.2%, 75.9%, and 76.7% for TRUS (P>0.05), while its specificity (72.2%) was significantly higher than that of MRI (44.4%) (P=0.03). The TRTE findings were not significantly correlated with the pathological findings and serum total prostate specific antigen (P>0.05), and the diagnostic sensitivity of TRTE decreased along with the enlargement of prostate. However, the diagnostic specificity of TRTE was higher than MRI for nodules with soft to medium texture (P=0.04).For PCa, the diagnostic sensitivity of TRTE increased when the Gleanson scores of tumors increased (P<0.05).</p><p><b>CONCLUSION</b>TRTE can be used as a diagnostic test to supplement clinical diagnosis of PCa.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias da Próstata
/
Reto
/
Diagnóstico por Imagem
/
Valor Preditivo dos Testes
/
Sensibilidade e Especificidade
/
Técnicas de Imagem por Elasticidade
/
Métodos
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Aged80
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2011
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS