Safety of recombinant human growth hormone in treating children with growth hormone deficiency and idiopathic short stature / 中国医学科学院学报

ABSTRACT

Recombinant human growth hormone is generally safe in treating children with growth hormone deficiency and idiopathic short stature. However, side effects such as sodium and water retention, benign intracranial hypertension, insulin insensitivity, increasing risk of secondary neoplasm, scoliosis, and slipped capital femoral epiphysis may occur occasionally, although the overall incidence remains low.