Impaired Global Right Ventricular Longitudinal Strain Predicts Long-Term Adverse Outcomes in Patients with Pulmonary Arterial Hypertension
Journal of Cardiovascular Ultrasound
;
: 91-99, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-34152
ABSTRACT
BACKGROUND:
New 2-dimensional strain echocardiography enables quantification of right ventricular (RV) mechanics by assessing global longitudinal strain of RV (GLSRV) in patients with pulmonary arterial hypertension (PAH). However, the prognostic significance of impaired GLSRV is unclear in these patients.METHODS:
Comprehensive echocardiography was performed in 51 consecutive PAH patients without atrial fibrillation (40 females, 48 +/- 14 years old) with long-term follow-up. GLSRV was measured with off-line with velocity vector imaging (VVI, Siemens Medical System, Mountain View, CA, USA).RESULTS:
GLSRV showed significant correlation with RV fractional area change (r = -0.606, p or = -15.5%) was associated with lower event-free survival (HR = 4.906, p = 0.001) and increased mortality (HR = 8.842, p = 0.005).CONCLUSION:
GLSRV by VVI showed significant correlations with conventional echocardiographic parameters indicating RV systolic function. Lower GLSRV (> or = -15.5%) was significantly associated with presence of adverse clinical events and deaths in PAH patients.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fibrilação Atrial
/
Resistência Vascular
/
Ecocardiografia
/
Análise Multivariada
/
Seguimentos
/
Mortalidade
/
Transplante de Pulmão
/
Intervalo Livre de Doença
/
Mecânica
/
Insuficiência Cardíaca
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Feminino
/
Humanos
Idioma:
Inglês
Revista:
Journal of Cardiovascular Ultrasound
Ano de publicação:
2015
Tipo de documento:
Artigo
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