Optimization of one-step pelletization technology of Jiuwei Xifeng granules by response surface methodology / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 4782-4786, 2014.
Artigo
em Chinês
| WPRIM
| ID: wpr-341816
ABSTRACT
Using the qualified rates of particles as the evaluation indexes, the impact tactors of one-step pelletization technology of Jiuwei Xifeng granules were selected from six factors by the Plackett-Burman experimental design and the levels of non-significant factors were identified. According to the Plackett-Burman experimental design, choosing the qualified rates of particles and angle of repose as the evaluation indexes, three levels of the three factors were selected by Box-Behnken of central composite design to optimize the experimental. The best conditions were as follows the fluid extract was sprayed with frequency of 29 r . min-1, inlet air temperature was 90 °C, the frequency of fan was 34 Hz. Under the response surface methodology optimized scheme, the average experimental results are similar to the predicted values, and surface methodology could be used in the optimization of one-step pelletization for Chinese materia medica.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Projetos de Pesquisa
/
Comprimidos
/
Medicamentos de Ervas Chinesas
/
Química
/
Análise de Variância
/
Movimentos do Ar
/
Composição de Medicamentos
/
Temperatura Alta
/
Métodos
/
Modelos Teóricos
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2014
Tipo de documento:
Artigo
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