Laparoscopy and digital subtraction angiography in the treatment of severe acute pancreatitis / 中华外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the effect of laparoscopy and digital subtraction angiography in the treatment of severe acute pancreatitis (SAP).</p><p><b>METHODS</b>Seventy-five SAP patients were randomly divided into tow groups (1) Conventional treatment group (group A, n = 35); (2) Conventional treatment combined with laparoscopy and digital subtraction angiography treatment group (group B, n = 40). The clinical parameters and treatment results in the 2 groups were compared.</p><p><b>RESULTS</b>After treatment, APACHE II score in group B was significantly lower than that in group A (P < 0.05). The functions of liver, renal and lung were recovered (P < 0.05, respectively), levels of serum TNF-alpha and IL-1 beta were significantly lower, but IL-10 significantly elevated (P < 0.05), the CT SPN was much lower (P < 0.05); rate of organ failure significantly decreased (P < 0.01), the successful rate of organ failure treatment was increased (P < 0.05); the in hospital mortality decreased (all P < 0.05).</p><p><b>CONCLUSIONS</b>Laparoscopy and digital subtraction angiography in combination with conventional treatment for SAP significantly improves the outcome and decrease the mortality of SAP.</p>