Advances in the study of steroidogenic acute regulatory protein / 中华男科学杂志
National Journal of Andrology
;
(12): 733-736, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-343531
ABSTRACT
The steroidogenic acute regulatory (StAR) protein is an essential component in the regulation of steroid biosynthesis in adrenal and gonadal cells. The StAR protein has a high tissue specificity, located on the mitochondrial membranes of some relative cells. It regulates the transfer of cholesterin from extracellular into intracellular and plays a dominant role in steroidogenic synthesis. Recent studies have also shown that the transcription and expression of StAR are modulated not only through the cAMP-PKA dependent pathway, but also by multiple hormones and cytokines, which contributes to the regulation of cholesterin synthesis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fosfoproteínas
/
Fisiologia
/
Enzima de Clivagem da Cadeia Lateral do Colesterol
/
Regulação da Expressão Gênica
/
Colesterol
/
Etisterona
/
Genética
/
Metabolismo
/
Mitocôndrias
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2006
Tipo de documento:
Artigo
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