Current situation of researches on the molecule mechanism of hormone refractory prostate cancer / 中华男科学杂志
National Journal of Andrology
;
(12): 551-554, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-343573
ABSTRACT
Most cases of prostate cancer become hormone refractory after 12 to 18 months of androgen deprivation therapy. The etiology of the disease is thought to be multifactorial, associated with genetic, dietary, and environmental factors. The article reviews the current situation of researches at home and abroad on the molecule mechanism of hormone refractory. It expounds the influence of the androgen receptor and its genetic mutation, apoptosis and the gene changes of p53, p21, EphB2 on prostate cancer. It is hoped to be of some directive value for the studies of prostate cancer.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Farmacologia
/
Neoplasias da Próstata
/
Receptores Androgênicos
/
Proteína Oncogênica p21(ras)
/
Genes p53
/
Apoptose
/
Receptor EphB2
/
Tratamento Farmacológico
/
Genética
Tipo de estudo:
Guia de Prática Clínica
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2006
Tipo de documento:
Artigo
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