Nuclear localization region in soluble adenylyl cyclase / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 280-284, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-343722
ABSTRACT
<p><b>OBJECTIVE</b>To locate the region responsible for nuclear localization of protein sAC.</p><p><b>METHODS</b>The eukaryotic expression vector of vairous sAC deletion mutants were transfected into Hela cells. The localization of each mutant was observed using confocal microscope.</p><p><b>RESULTS</b>For some mutants, the localization of sAC changed. Deletion of some region made it unable to locate in the nuclear.</p><p><b>CONCLUSION</b>It is possible to figure out that the nucleotide region (739-1038 and 1045-1261) take charge of nuclear localization of sAC.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Proteínas Nucleares
/
Adenilil Ciclases
/
Testes Genéticos
/
Microscopia Confocal
/
Predisposição Genética para Doença
/
Polimorfismo de Nucleotídeo Único
/
Diabetes Mellitus Tipo 2
/
Genética
Limite:
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2005
Tipo de documento:
Artigo
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